We offer Yeast Display Peptide Library Screening services based on a collection of premade high-diversity peptide libraries. These libraries enable efficient identification of peptide ligands for a wide range of applications, including receptor targeting, masking peptide discovery, and ligand development for receptor-directed conjugates (RDC).

Using our ready-to-screen libraries and optimized screening workflows, peptide binder discovery projects can typically be completed within a few weeks.

We provide several types of preconstructed yeast display peptide libraries designed to support diverse discovery applications.

Linear Peptide Libraries

Linear peptide libraries provide broad sequence diversity and are suitable for general ligand discovery and epitope exploration.

Monocyclic Peptide Libraries

These libraries contain peptides constrained by a single disulfide bond, improving structural stability and binding affinity.

Bicyclic Peptide Libraries

Bicyclic peptide libraries contain two disulfide bonds that create highly constrained structures, enabling the discovery of high-affinity binders with enhanced stability and specificity.

Our peptide discovery workflow integrates yeast display technology with high-throughput screening and sequence analysis.

To confirm screening results, selected peptide candidates can undergo preliminary validation.

Typical validation steps include:

Peptide synthesis

ELISA-based binding assays

Flow cytometry binding analysis

Competitive binding assays (for masking peptide discovery)

These experiments help confirm target binding and support further development of peptide candidates.

Clients will receive:

Target-binding peptide sequences

Sequence enrichment analysis

Comprehensive screening report

Candidate peptide synthesis (optional)

Preliminary binding validation data(optional)

Optional downstream services include functional characterization.